Molecular and Cellular Pediatrics volume 9, Article number: 6 (2022) Published: 05 April 2022

• PMID: 21051046
• DOI:https://doi.org/10.1186/s40348-022-00139-x

Abstract

Background: Exclusive enteral nutrition (EEN) is the first-line therapy for pediatric-onset Crohn’s disease (CD) patients. CEDATA-GPGE® is the largest patient registry for children and adolescents with inflammatory bowel disease (IBD) in Europe, collecting data from over 5000 patients since 2004 in Germany and Austria. Since the application of EEN over 8 weeks is difficult and a high dropout rate is often described, the mode of application including a supporting structure is crucial for success. The aim of this study was to ascertain the variation in the application of EEN across the participating centers and to associate these with the outcome.

Results: Thirty-one centers responded to the survey (81.6%). 88.5% of CD patients were recommended EEN for induction therapy, 71.8% actually started with EEN, and 22.1% terminated the EEN prematurely. The duration of EEN typically lasted 6 to 8 weeks, and the polymeric formula was mainly used. 80.6% of the clinics added flavorings to the formulas. After EEN, the most preferred diet for maintenance therapy was a healthy, well-balanced diet considering individual intolerances.

Conclusions: EEN is widely recommended as an induction therapy by the German and Austrian pediatric gastroenterologists for children and adolescents with CD. However, this questionnaire-based study has shown a wide variation in EEN protocols used by the different pediatric clinics of CEDATA-GPGE®.

© 2023 BioMed Central Ltd unless otherwise stated. Part of Springer Nature.

Der Beitrag Implementation of exclusive enteral nutrition in pediatric patients with Crohn’s disease—results of a survey of CEDATA-GPGE reporting centers erschien zuerst auf CEDATA GPGE – Patientenregister.

D. Scholz, R. Behrens, M. Claßen

Kinder- und Jugendmedizin 2011; 11: 283–288,  Schattauer 5/2011: 1-6
Patient registries as epidemiologic tools – the inflammatory bowel disease registry CEDATA-GPGE

Summary

With the incidence of inflammatory bowel disease (IBD), especially Crohn’s disease of childhood and adolescence, on the rise, science has focused attention on the characteristics of paediatric IBD. Longer periods of illness, pain, underweight and more impair the physical, emotional, and intellectual development. Paediatricians should be familiar with the natural course and complications of pediatric IBD in order to assist their patients in reaching their full potential. Patient registries have been set up in many western countries, but due to institutional constraints often cover only a part of the population. In 2000 the Saxonian Children-IBD-registry has been instituted, a state-wide documentation system for the course of IBD in pediatric patients. Building on this expertise in 2004 the German-Language Society of Paediatric Gastroenterology and Nutrition (GPGE) established the registry CEDATA that meanwhile included the largest cohort of children and adolescents with IBD worldwide.

Der Beitrag Patientenregister als epidemiologische Werkzeuge erschien zuerst auf CEDATA GPGE – Patientenregister.